8HNL: CXCR3-DNGi complex activated by PS372424

PDB ID: 8HNLDownload
MMDB ID: 239155
PDB Deposition Date: 2022/12/8
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 2.98  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8HNL: pentameric; determined by author
Molecular Components in 8HNL
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Soluble Cytochrome B562,c-x-c Chemokine Receptor Type 3,oplophorus-luciferin 2-monooxygenase Catalytic Subunit
Molecule annotation
1
Single-chain Variable Fragment Scfv16
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CHOLESTEROLCHOLESTEROL
2
1
(3S)-N-[(2S)-5-carbamimidamido-1-(cyclohexylmethylamino)-1-oxidanylidene-pentan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide(3S)-N-[(2S)-5-carbamimidamido-1-(cyclohexylmethylamino)-1-oxidanylidene-pentan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303