8HMY: Cryo-EM structure of the human pre-catalytic TSEN/pre-tRNA complex

PDB ID: 8HMYDownload
MMDB ID: 229298
PDB Deposition Date: 2022/12/6
Updated in MMDB: 2025/08
Experimental Method:
electron microscopy
Resolution: 2.94  Å
Source Organism:
Similar Structures:
Biological Unit for 8HMY: hexameric; determined by author
Molecular Components in 8HMY
Label Count Molecule
Proteins (5 molecules)
1
tRNA-splicing Endonuclease Subunit Sen2
(Gene symbol: TSEN2)
Molecule annotation
1
tRNA-splicing Endonuclease Subunit Sen34
(Gene symbol: TSEN34)
Molecule annotation
1
tRNA-splicing Endonuclease Subunit Sen54
(Gene symbol: TSEN54)
Molecule annotation
1
Chromosome 1 Open Reading Frame 19, Isoform Cra_a
(Gene symbol: TSEN15)
Molecule annotation
1
Polyribonucleotide 5'-hydroxyl-kinase Clp1
(Gene symbol: CLP1)
Molecule annotation
Nucleotide(1 molecule)
1
Pre-trna
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
6
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303