8HMT: The complex of ACK1 with the inhibitor 2-142

PDB ID: 8HMTDownload
MMDB ID: 239714
PDB Deposition Date: 2022/12/5
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.17  Å
Source Organism:
Similar Structures:
Biological Unit for 8HMT: monomeric; determined by author
Molecular Components in 8HMT
Label Count Molecule
Protein (1 molecule)
1
Activated Cdc42 Kinase 1
(Gene symbol: TNK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-(2-bromophenyl)-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[[(2S)-oxolan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one6-(2-bromophenyl)-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[[(2S)-oxolan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303