8HMP: GPR52 with Gs and c17

PDB ID: 8HMPDownload
MMDB ID: 231951
PDB Deposition Date: 2022/12/5
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 2.77  Å
Source Organism:
Similar Structures:
Biological Unit for 8HMP: pentameric; determined by author
Molecular Components in 8HMP
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Nb35
Molecule annotation
1
G-protein Coupled Receptor 52
(Gene symbol: GPR52)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
(Gene symbol: GNAS)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(2-hydroxyethyl)-5-(hydroxymethyl)-3-methyl-1-[2-[[3-(trifluoromethyl)phenyl]methyl]-1-benzothiophen-7-yl]pyrazole-4-carboxamideN-(2-hydroxyethyl)-5-(hydroxymethyl)-3-methyl-1-[2-[[3-(trifluoromethyl)phenyl]methyl]-1-benzothiophen-7-yl]pyrazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303