8HMB: Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with benidipine (BEN)

PDB ID: 8HMBDownload
MMDB ID: 245734
PDB Deposition Date: 2022/12/2
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8HMB: trimeric; determined by author
Molecular Components in 8HMB
Label Count Molecule
Proteins (3 molecules)
1
Isoform 2C of Voltage-dependent L-type Calcium Channel Subunit Beta-2
(Gene symbol: CACNB2)
Molecule annotation
1
Voltage-dependent L-type Calcium Channel Subunit Alpha
(Gene symbol: CACNA1C)
Molecule annotation
1
Voltage-dependent Calcium Channel Subunit Alpha-2/delta-1
(Gene symbol: CACNA2D1)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
8
HEXADECANEHEXADECANE
2
3
1,2-Distearoyl-sn-glycerophosphoethanolamine1,2-Distearoyl-sn-glycerophosphoethanolamine
3
1
HEXADECANEHEXADECANE
4
2
CALCIUM IONCALCIUM ION
5
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303