8HLQ: Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Niraparib (MK-4827)

PDB ID: 8HLQDownload
MMDB ID: 246029
PDB Deposition Date: 2022/11/30
Updated in MMDB: 2025/05
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 8HLQ: monomeric; determined by author and by software (PISA)
Molecular Components in 8HLQ
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 2
(Gene symbol: PARP2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
GLYCEROLGLYCEROL
2
1
2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303