8HLP: Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo)

PDB ID: 8HLPDownload
MMDB ID: 245732
PDB Deposition Date: 2022/11/30
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8HLP: trimeric; determined by author
Molecular Components in 8HLP
Label Count Molecule
Proteins (3 molecules)
1
Voltage-dependent L-type Calcium Channel Subunit Alpha
(Gene symbol: CACNA1C)
Molecule annotation
1
Voltage-dependent Calcium Channel Subunit Alpha-2/delta-1
(Gene symbol: CACNA2D1)
Molecule annotation
1
Isoform 2C of Voltage-dependent L-type Calcium Channel Subunit Beta-2
(Gene symbol: CACNB2)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
9
HEXADECANEHEXADECANE
2
2
1,2-Distearoyl-sn-glycerophosphoethanolamine1,2-Distearoyl-sn-glycerophosphoethanolamine
3
2
CALCIUM IONCALCIUM ION
4
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303