8HLJ: Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Olaparib (AZD2281)

PDB ID: 8HLJDownload
MMDB ID: 246028
PDB Deposition Date: 2022/11/30
Updated in MMDB: 2025/05
Experimental Method:
x-ray diffraction
Resolution: 2.24  Å
Source Organism:
Similar Structures:
Biological Unit for 8HLJ: monomeric; determined by author
Molecular Components in 8HLJ
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 2
(Gene symbol: PARP2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303