8HJE: Vismodegib binds to the catalytical domain of human Ubiquitin-Specific Protease 28

PDB ID: 8HJEDownload
MMDB ID: 229846
PDB Deposition Date: 2022/11/23
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.85  Å
Source Organism:
Similar Structures:
Biological Unit for 8HJE: monomeric; determined by author
Molecular Components in 8HJE
Label Count Molecule
Protein (1 molecule)
1
Ubiquitin Carboxyl-terminal Hydrolase 28
(Gene symbol: USP28)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303