8HJ5: Cryo-EM structure of Gq-coupled MRGPRX1 bound with Compound-16

PDB ID: 8HJ5Download
MMDB ID: 230952
PDB Deposition Date: 2022/11/22
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8HJ5: hexameric; determined by author
Molecular Components in 8HJ5
Label Count Molecule
Proteins (6 molecules)
1
Guanine Nucleotide-binding Protein G(q) Subunit Alpha
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Scfv16
Molecule annotation
1
Soluble Cytochrome B562,mas-related G-protein Coupled Receptor Member X1,lgbit
Molecule annotation
1
Nb35
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{2-[(1-aminoisoquinolin-6-yl)oxy]-4-methylphenyl}-2-methoxybenzene-1-sulfonamideN-{2-[(1-aminoisoquinolin-6-yl)oxy]-4-methylphenyl}-2-methoxybenzene-1-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303