8HHP: Crystal structure of PPARg-LBD complexed with three partial agonists, one nTZDpa and two LT175

PDB ID: 8HHPDownload
MMDB ID: 238757
PDB Deposition Date: 2022/11/16
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 8HHP: monomeric; determined by author and by software (PISA)
Molecular Components in 8HHP
Label Count Molecule
Protein (1 molecule)
1
Peroxisome Proliferator-activated Receptor Gamma
(Gene symbol: PPARG)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID
2
2
(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303