8HEJ: Crystal structure of Transthyretin in complex with a covalent inhibitor trans-styrylpyrazole

PDB ID: 8HEJDownload
MMDB ID: 238474
PDB Deposition Date: 2022/11/8
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.54  Å
Source Organism:
Similar Structures:
Biological Unit for 8HEJ: tetrameric; determined by author
Molecular Components in 8HEJ
Label Count Molecule
Proteins (4 molecules)
4
Transthyretin
(Gene symbol: TTR)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
2,6-dibromo-4-[(E)-2-(3,5-dimethyl-1H-pyrazol-4-yl)ethenyl]phenol2,6-dibromo-4-[(E)-2-(3,5-dimethyl-1H-pyrazol-4-yl)ethenyl]phenol
2
4
2,4,6-trifluorobenzaldehyde2,4,6-trifluorobenzaldehyde
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303