8HBF: Structure of human soluble guanylate cyclase in the NO+Rio state at 3.1 angstrom

PDB ID: 8HBFDownload
MMDB ID: 229294
PDB Deposition Date: 2022/10/28
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 8HBF: dimeric; determined by author
Molecular Components in 8HBF
Label Count Molecule
Proteins (2 molecules)
1
Guanylate Cyclase Soluble Subunit Alpha-1
(Gene symbol: GUCY1A1)
Molecule annotation
1
Guanylate Cyclase Soluble Subunit Beta-1
(Gene symbol: GUCY1B1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
4
1
methyl ~{N}-[4,6-bis(azanyl)-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]-~{N}-methyl-carbamatemethyl ~{N}-[4,6-bis(azanyl)-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]-~{N}-methyl-carbamate
5
1
NITRIC OXIDENITRIC OXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303