8HB0: Structure of human SGLT2-MAP17 complex with TA1887

PDB ID: 8HB0Download
MMDB ID: 237468
PDB Deposition Date: 2022/10/27
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8HB0: dimeric; determined by author
Molecular Components in 8HB0
Label Count Molecule
Proteins (2 molecules)
1
Sodium/glucose Cotransporter 2
(Gene symbol: SLC5A2)
Molecule annotation
1
Pdzk1-interacting Protein 1
(Gene symbol: PDZK1IP1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
(2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol(2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol
3
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303