8H37: Cryo-EM Structure of the KBTBD2-CUL3-Rbx1-p85a tetrameric complex

PDB ID: 8H37Download
MMDB ID: 236610
PDB Deposition Date: 2022/10/8
Updated in MMDB: 2023/10
Experimental Method:
electron microscopy
Resolution: 7.52  Å
Source Organism:
Similar Structures:
Biological Unit for 8H37: hexadecameric; determined by author
Molecular Components in 8H37
Label Count Molecule
Proteins (16 molecules)
4
Cullin-3
(Gene symbol: CUL3)
Molecule annotation
4
E3 Ubiquitin-protein Ligase Rbx1
(Gene symbol: RBX1)
Molecule annotation
4
Kelch Repeat and BTB Domain-containing Protein 2
(Gene symbol: KBTBD2)
Molecule annotation
4
Phosphatidylinositol 3-kinase Regulatory Subunit Alpha
(Gene symbol: PIK3R1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
12
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303