8GW8: the human PTH1 receptor bound to an intracellular biased agonist

PDB ID: 8GW8Download
MMDB ID: 231717
PDB Deposition Date: 2022/9/16
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
unidentified▼
Similar Structures:
Biological Unit for 8GW8: pentameric; determined by author
Molecular Components in 8GW8
Label Count Molecule
Proteins (5 molecules)
1
Isoform Gnas-2 of Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody-35
Molecule annotation
1
Parathyroid Hormone/parathyroid Hormone-related Peptide Receptor
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
PCO-371PCO-371
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303