8GW1: A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors

PDB ID: 8GW1Download
MMDB ID: 241870
PDB Deposition Date: 2022/9/16
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 3.31  Å
Source Organism:
Similar Structures:
Biological Unit for 8GW1: nonameric; determined by author
Molecular Components in 8GW1
Label Count Molecule
Proteins (7 molecules)
1
Replicase Polyprotein 1AB
Molecule annotation
2
Non-structural Protein 8
Molecule annotation
1
Non-structural Protein 7
Molecule annotation
2
Helicase
Molecule annotation
1
Non-structural Protein 9
Molecule annotation
Nucleotides(2 molecules)
1
RNA (25-mer)
Molecule annotation
1
Template
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
8
ZINC IONZINC ION
2
2
MANGANESE (II) IONMANGANESE (II) ION
3
1
URIDINE-5'-MONOPHOSPHATEURIDINE-5'-MONOPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303