8GVZ: Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil

PDB ID: 8GVZDownload
MMDB ID: 235826
PDB Deposition Date: 2022/9/16
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 8GVZ: monomeric; determined by author
Molecular Components in 8GVZ
Label Count Molecule
Protein (1 molecule)
1
CAD Protein
(Gene symbol: CAD)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
5-FLUOROURACIL5-FLUOROURACIL
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303