8GVX: Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class2

PDB ID: 8GVXDownload
MMDB ID: 230614
PDB Deposition Date: 2022/9/16
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.91  Å
Source Organism:
Similar Structures:
Biological Unit for 8GVX: octameric; determined by author
Molecular Components in 8GVX
Label Count Molecule
Proteins (8 molecules)
4
Short Transient Receptor Potential Channel 5
(Gene symbol: TRPC5)
Molecule annotation
4
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-3
(Gene symbol: GNAI3)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
4
PHOSPHATIDYLETHANOLAMINEPHOSPHATIDYLETHANOLAMINE
2
4
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
3
4
ZINC IONZINC ION
4
4
CALCIUM IONCALCIUM ION
5
4
(2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate(2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate
6
4
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303