8GVW: Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class2

PDB ID: 8GVWDownload
MMDB ID: 230613
PDB Deposition Date: 2022/9/16
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.59  Å
Source Organism:
Similar Structures:
Biological Unit for 8GVW: tetrameric; determined by author
Molecular Components in 8GVW
Label Count Molecule
Proteins (4 molecules)
4
Short Transient Receptor Potential Channel 5
(Gene symbol: TRPC5)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
4
PHOSPHATIDYLETHANOLAMINEPHOSPHATIDYLETHANOLAMINE
2
4
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
3
4
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
4
4
ZINC IONZINC ION
5
4
CALCIUM IONCALCIUM ION
6
4
(2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate(2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303