8GT7: Structure of falcipain and human Stefin A mutant complex

PDB ID: 8GT7Download
MMDB ID: 235428
PDB Deposition Date: 2022/9/7
Updated in MMDB: 2025/09
Experimental Method:
x-ray diffraction
Resolution: 3.28  Å
Source Organism:
Plasmodium falciparum 3D7▼
Similar Structures:
Biological Unit for 8GT7: hexameric; determined by author
Molecular Components in 8GT7
Label Count Molecule
Proteins (6 molecules)
2
Cysteine Proteinase Falcipain 2A
Molecule annotation
2
Cystatin-a
Molecule annotation
1
Lys-glu-ile-val-asn-pro-leu-thr-lys
Molecule annotation
1
Val-asn-pro-leu-thr-lys-lys-gly-glu
Molecule annotation
Chemicals and Non-standard biopolymers (236 molecules)
1
65
GLYCEROLGLYCEROL
2
44
SODIUM IONSODIUM ION
3
48
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
4
5
SULFATE IONSULFATE ION
5
54
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
6
12
3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL
7
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303