8GRQ: Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome

PDB ID: 8GRQDownload
MMDB ID: 229012
PDB Deposition Date: 2022/9/2
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 3.87  Å
Source Organism:
Similar Structures:
Biological Unit for 8GRQ: tridecameric; determined by author
Molecular Components in 8GRQ
Label Count Molecule
Proteins (11 molecules)
2
Histone H3
Molecule annotation
2
Histone H4
Molecule annotation
2
Histone H2A Type 1-H
Molecule annotation
2
H2B
Molecule annotation
1
Breast Cancer Type 1 Susceptibility Protein
(Gene symbol: BRCA1)
Molecule annotation
1
Brca1-associated Ring Domain Protein 1
(Gene symbol: BARD1)
Molecule annotation
1
Ubiquitin-conjugating Enzyme E2D 3 (Ubc4/5 Homolog, Yeast), Isoform Cra_a
(Gene symbol: UBE2D3)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (147-mer)
Molecule annotation
1
DNA (147-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
4
* Click molecule labels to explore molecular sequence information.

Citing MMDB