8GNG: Crystal structure of human adenosine A2A receptor in complex with istradefylline

PDB ID: 8GNGDownload
MMDB ID: 228161
PDB Deposition Date: 2022/8/23
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8GNG: trimeric; determined by author
Molecular Components in 8GNG
Label Count Molecule
Proteins (3 molecules)
1
Adenosine Receptor A2A
Molecule annotation
1
Antibody FAB Fragment Light Chain
Molecule annotation
1
Antibody FAB Fragment Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione
2
7
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
3
2
CHLORIDE IONCHLORIDE ION
4
1
POTASSIUM IONPOTASSIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303