8GMN: Crystal structure of human C1s in complex with inhibitor

PDB ID: 8GMNDownload
MMDB ID: 230292
PDB Deposition Date: 2023/3/26
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8GMN: monomeric; determined by software (PISA)
Molecular Components in 8GMN
Label Count Molecule
Protein (1 molecule)
1
Complement C1S Subcomponent
(Gene symbol: C1S)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
[4-(1-aminophthalazin-6-yl)piperazin-1-yl](2-methylphenyl)methanone[4-(1-aminophthalazin-6-yl)piperazin-1-yl](2-methylphenyl)methanone
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303