8GML: Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dG

PDB ID: 8GMLDownload
MMDB ID: 235815
PDB Deposition Date: 2023/3/26
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.567  Å
Source Organism:
Similar Structures:
Biological Unit for 8GML: trimeric; determined by author and by software (PISA)
Molecular Components in 8GML
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase ETA
(Gene symbol: POLH)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(p*tp*gp*cp*tp*cp*ap*cp*ap*cp*t)-3')
Molecule annotation
1
DNA (5'-d(*ap*gp*tp*gp*tp*gp*ap*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate)2'-deoxy-5-fluorouridine 5'-(tetrahydrogen triphosphate)
2
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303