8GLS: Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and Z1834339853

PDB ID: 8GLSDownload
MMDB ID: 248729
PDB Deposition Date: 2023/3/23
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8GLS: dimeric; determined by author
Molecular Components in 8GLS
Label Count Molecule
Proteins (2 molecules)
1
Cystic Fibrosis Transmembrane Conductance Regulator
(Gene symbol: CFTR)
Molecule annotation
1
Human Cystic Fibrosis Transmembrane Conductance Regulator
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
3
5
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
4
1
(2S)-1-(3-amino-6-fluoro-1H-indazol-1-yl)-2-methyl-3-phenoxypropan-1-one(2S)-1-(3-amino-6-fluoro-1H-indazol-1-yl)-2-methyl-3-phenoxypropan-1-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303