8GIS: Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.5mM Mn2+

PDB ID: 8GISDownload
MMDB ID: 245348
PDB Deposition Date: 2023/3/14
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.46  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8GIS: hexameric; determined by author and by software (PISA)
Molecular Components in 8GIS
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
Molecule annotation
Nucleotides(4 molecules)
4
Palindromic Dna18
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
2
ZINC IONZINC ION
3
4
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303