8GFT: Hsp90 provides platform for CRaf dephosphorylation by PP5

PDB ID: 8GFTDownload
MMDB ID: 229837
PDB Deposition Date: 2023/3/8
Updated in MMDB: 2023/05
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8GFT: pentameric; determined by author
Molecular Components in 8GFT
Label Count Molecule
Proteins (5 molecules)
2
Heat Shock Protein HSP 90-beta
(Gene symbol: HSP90AB1)
Molecule annotation
1
Hsp90 Co-chaperone Cdc37, N-terminally Processed
(Gene symbol: CDC37)
Molecule annotation
1
RAF Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: RAF1)
Molecule annotation
1
Serine/threonine-protein Phosphatase 5
(Gene symbol: PPP5C)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
POTASSIUM IONPOTASSIUM ION
4
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
5
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303