8GEG: CryoEM structure of beta-2-adrenergic receptor in complex with nucleotide-free Gs heterotrimer (#17 of 20)

PDB ID: 8GEGDownload
MMDB ID: 243557
PDB Deposition Date: 2023/3/6
Updated in MMDB: 2024/06
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8GEG: tetrameric; determined by author
Molecular Components in 8GEG
Label Count Molecule
Proteins (4 molecules)
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
(Gene symbol: GNAS)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Beta-2 Adrenergic Receptor
(Gene symbol: ADRB2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol(5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303