8GDC: Cryo-EM Structure of the Prostaglandin E2 Receptor 3 Coupled to G Protein

PDB ID: 8GDCDownload
MMDB ID: 241000
PDB Deposition Date: 2023/3/3
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8GDC: tetrameric; determined by author
Molecular Components in 8GDC
Label Count Molecule
Proteins (4 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
(Gene symbol: GNAI1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein Subunit Gamma
Molecule annotation
1
Prostaglandin E2 Receptor EP3 Subtype
(Gene symbol: PTGER3)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303