8GD9: Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein

PDB ID: 8GD9Download
MMDB ID: 240997
PDB Deposition Date: 2023/3/3
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Lama glama▼
Similar Structures:
Biological Unit for 8GD9: pentameric; determined by author
Molecular Components in 8GD9
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein Subunit Gamma
Molecule annotation
1
Nb35
Molecule annotation
1
Prostaglandin E2 Receptor EP4 Subtype
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-({2-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]butyl}cyclopentyl]ethyl}sulfanyl)butanoic acid4-({2-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]butyl}cyclopentyl]ethyl}sulfanyl)butanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303