8GD7: Loop Deleted DNA Polymerase Theta Polymerase Domain in Complex with Double Strand DNA Overhang and Inhibitor

PDB ID: 8GD7Download
MMDB ID: 248406
PDB Deposition Date: 2023/3/3
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 3.24  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8GD7: trimeric; determined by author and by software (PISA)
Molecular Components in 8GD7
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase Theta
Molecule annotation
Nucleotides(2 molecules)
1
DNA Template
Molecule annotation
1
DNA Primer
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE
3
1
2-(3-methyl-2-oxoimidazolidin-1-yl)-4,6-bis(trifluoromethyl)phenyl (4-fluorophenyl)methylcarbamate2-(3-methyl-2-oxoimidazolidin-1-yl)-4,6-bis(trifluoromethyl)phenyl (4-fluorophenyl)methylcarbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303