8GC5: Domoate-bound GluK2 kainate receptors in non-active conformation

PDB ID: 8GC5Download
MMDB ID: 243917
PDB Deposition Date: 2023/3/1
Updated in MMDB: 2025/09
Experimental Method:
electron microscopy
Resolution: 3.93  Å
Source Organism:
Similar Structures:
Biological Unit for 8GC5: tetrameric; determined by author
Molecular Components in 8GC5
Label Count Molecule
Proteins (4 molecules)
4
Glutamate Receptor Ionotropic, Kainate 2
(Gene symbol: Grik2)
Molecule annotation
Chemicals and Non-standard biopolymers (44 molecules)
1
22
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
6
beta-D-mannopyranosebeta-D-mannopyranose
3
12
alpha-D-mannopyranosealpha-D-mannopyranose
4
4
(2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID(2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303