8GBF: Crystal structure of human DNA polymerase eta incorporating syn-ITP across dT

PDB ID: 8GBFDownload
MMDB ID: 243230
PDB Deposition Date: 2023/2/25
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.11  Å
Source Organism:
Similar Structures:
Biological Unit for 8GBF: trimeric; determined by author and by software (PISA)
Molecular Components in 8GBF
Label Count Molecule
Protein (1 molecule)
1
DNA Polymerase ETA
(Gene symbol: POLH)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(p*ap*tp*tp*cp*tp*cp*ap*cp*ap*cp*t)-3')
Molecule annotation
1
DNA (5'-d(*ap*gp*tp*gp*tp*gp*ap*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
[[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(6-oxidanylidene-1~{H}-purin-9-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate[[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(6-oxidanylidene-1~{H}-purin-9-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
2
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303