8GAN: Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications

PDB ID: 8GANDownload
MMDB ID: 243533
PDB Deposition Date: 2023/2/23
Updated in MMDB: 2024/03
Experimental Method:
electron microscopy
Resolution: 3.26  Å
Source Organism:
Similar Structures:
Molecular Components in 8GAN
Label Count Molecule
Proteins (12 molecules)
7
Cas7
Molecule annotation
3
Cas11
Molecule annotation
1
Cas8
Molecule annotation
1
Cas5
Molecule annotation
Nucleotides(4 molecules)
1
Crrna (43-mer)
Molecule annotation
1
Target Strand DNA (53-mer)
Molecule annotation
1
Proximal NON Target Strand DNA (5'-d(p*ap*tp*gp*ap*ap*cp*tp*tp*cp*ap*ap*ap*ap*ap*ap*ap*ap*ap*a)-3')
Molecule annotation
1
Distal NON Target Strand DNA (5'-d(p*ap*tp*tp*ap*tp*ap*tp*tp*ap*ap*tp*ap*tp*tp*ap*tp*ap*tp*tp*tp*a)-3')
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303