8GAG: Cannabinoid receptor 1-Gi complex with novel ligand

PDB ID: 8GAGDownload
MMDB ID: 243226
PDB Deposition Date: 2023/2/22
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8GAG: pentameric; determined by author and by software
Molecular Components in 8GAG
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Cannabinoid Receptor 1
Molecule annotation
1
Scfv16
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
methyl (2R)-2-({(1M)-5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonyl}amino)-2-(thiophen-2-yl)propanoatemethyl (2R)-2-({(1M)-5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonyl}amino)-2-(thiophen-2-yl)propanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303