8G9Q: Tricomplex of Compound-1, KRAS G12C, and CypA

PDB ID: 8G9QDownload
MMDB ID: 234225
PDB Deposition Date: 2023/2/21
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8G9Q: dimeric; determined by author and by software (PISA)
Molecular Components in 8G9Q
Label Count Molecule
Proteins (2 molecules)
1
Gtpase Kras
(Gene symbol: KRAS)
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase a
(Gene symbol: PPIA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
methyl (3S)-1-[N-(4-sulfanylbutanoyl)-L-valyl-3-hydroxy-L-phenylalanyl]-1,2-diazinane-3-carboxylatemethyl (3S)-1-[N-(4-sulfanylbutanoyl)-L-valyl-3-hydroxy-L-phenylalanyl]-1,2-diazinane-3-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303