8G6I: Coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor

PDB ID: 8G6IDownload
MMDB ID: 230584
PDB Deposition Date: 2023/2/15
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 4.23  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8G6I: trimeric; determined by author
Molecular Components in 8G6I
Label Count Molecule
Proteins (3 molecules)
1
Coagulation Factor Viii Chimera From Human and PIG
Molecule annotation
1
Nb33 Light Chain
Molecule annotation
1
Nb33 Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303