8G5G: Native GABA-A receptor from the mouse brain, meta-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA, Zolpidem, and endogenous neurosteroid

PDB ID: 8G5GDownload
MMDB ID: 235801
PDB Deposition Date: 2023/2/13
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 2.94  Å
Source Organism:
Similar Structures:
Biological Unit for 8G5G: heptameric; determined by author
Molecular Components in 8G5G
Label Count Molecule
Proteins (7 molecules)
1
Gamma-aminobutyric Acid Receptor Subunit Alpha-1
Molecule annotation
2
Gamma-aminobutyric Acid Receptor Subunit Beta-2
Molecule annotation
1
Gamma-aminobutyric Acid Receptor Subunit Gamma-2
Molecule annotation
1
Heavy Chain of 8E3 FAB
Molecule annotation
1
Light Chain of 8E3 FAB
Molecule annotation
1
Gamma-aminobutyric Acid Receptor Subunit Alpha-3
Molecule annotation
Chemicals and Non-standard biopolymers (41 molecules)
1
15
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
7
beta-D-mannopyranosebeta-D-mannopyranose
3
12
alpha-D-mannopyranosealpha-D-mannopyranose
4
1
alpha-L-fucopyranosealpha-L-fucopyranose
5
2
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
6
1
allopregnanoloneallopregnanolone
7
2
GAMMA-AMINO-BUTANOIC ACIDGAMMA-AMINO-BUTANOIC ACID
8
1
ZolpidemZolpidem
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303