8G47: KRAS G12C complex with GDP and AMG 510 imaged on a cryo-EM imaging scaffold

PDB ID: 8G47Download
MMDB ID: 233874
PDB Deposition Date: 2023/2/8
Updated in MMDB: 2023/10
Experimental Method:
electron microscopy
Resolution: 3.19  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8G47: dimeric; determined by author
Molecular Components in 8G47
Label Count Molecule
Proteins (2 molecules)
1
Rcg-33 - Cryo-em Imaging Scaffold Subunit B Fused to Darpin
Molecule annotation
1
Gtpase Kras
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
3
1
AMG 510 (bound form)AMG 510 (bound form)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303