8G45: Structure of HDAC6 zinc-finger ubiquitin binding domain in complex with SGC-UBD253 chemical probe

PDB ID: 8G45Download
MMDB ID: 229831
PDB Deposition Date: 2023/2/8
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 1.62  Å
Source Organism:
Similar Structures:
Biological Unit for 8G45: monomeric; determined by author
Molecular Components in 8G45
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 6
(Gene symbol: HDAC6)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
3
ZINC IONZINC ION
2
1
3-[8-chloro-3-(2-{[(2-methoxyphenyl)methyl]amino}-2-oxoethyl)-4-oxo-3,4-dihydroquinazolin-2-yl]propanoic acid3-[8-chloro-3-(2-{[(2-methoxyphenyl)methyl]amino}-2-oxoethyl)-4-oxo-3,4-dihydroquinazolin-2-yl]propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303