8G3T: MBP-Mcl1 in complex with ligand 12

PDB ID: 8G3TDownload
MMDB ID: 230284
PDB Deposition Date: 2023/2/8
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.83  Å
Source Organism:
Similar Structures:
Biological Unit for 8G3T: monomeric; determined by author
Molecular Components in 8G3T
Label Count Molecule
Protein (1 molecule)
1
Maltodextrin-binding Protein, Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 Chimera
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
FORMIC ACIDFORMIC ACID
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
(1'S,3aS,5R,16R,17S,19Z,21R,21aR)-6'-chloro-20-fluoro-21-methoxy-16,17-dimethyl-2,3,3',3a,4',16,17,18,21,21a-decahydro-2'H,6H,8H-15lambda~6~-spiro[10,12-etheno-15lambda~6~-furo[3,2-i][1,4]oxazepino[3,4-f][1,2,7]thiadiazacyclohexadecine-7,1'-naphthalene]-13,15,15(4H,14H)-trione(1'S,3aS,5R,16R,17S,19Z,21R,21aR)-6'-chloro-20-fluoro-21-methoxy-16,17-dimethyl-2,3,3',3a,4',16,17,18,21,21a-decahydro-2'H,6H,8H-15lambda~6~-spiro[10,12-etheno-15lambda~6~-furo[3,2-i][1,4]oxazepino[3,4-f][1,2,7]thiadiazacyclohexadecine-7,1'-naphthalene]-13,15,15(4H,14H)-trione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303