8G2M: The tumor activated anti-CTLA-4 monoclonal antibody XTX101 demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer

PDB ID: 8G2MDownload
MMDB ID: 242588
PDB Deposition Date: 2023/2/5
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Peptide display vector fth1▼
Similar Structures:
Biological Unit for 8G2M: trimeric; determined by author and by software (PISA)
Molecular Components in 8G2M
Label Count Molecule
Proteins (3 molecules)
1
Masking Peptide
Molecule annotation
1
Heavy Chain of Humanized IGG
Molecule annotation
1
Light Chain of Humanized IGG
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
CITRIC ACIDCITRIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303