8G10: Structure of Ternary Complex of cGAS with dsDNA and Bound ITP and GTP

PDB ID: 8G10Download
MMDB ID: 247175
PDB Deposition Date: 2023/2/1
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.47  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8G10: hexameric; determined by author and by software (PISA)
Molecular Components in 8G10
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
Molecule annotation
Nucleotides(4 molecules)
4
Palindromic Dna18
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303