8G0H: Human PARP1 deltaV687-E688 bound to UKTT5 (compound 10) and to a DNA double strand break

PDB ID: 8G0HDownload
MMDB ID: 242251
PDB Deposition Date: 2023/1/31
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 3.8  Å
Source Organism:
DNA molecule▼
Similar Structures:
Biological Unit for 8G0H: tetrameric; determined by author and by software (PISA)
Molecular Components in 8G0H
Label Count Molecule
Proteins (2 molecules)
1
Poly [adp-ribose] Polymerase 1
Molecule annotation
1
Fusion of Human Parp1 Zinc Fingers 1 and 3 (Zn1, Zn3),poly [adp-ribose] Polymerase 1
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*cp*gp*ap*cp*g)-3')
Molecule annotation
1
DNA (5'-d(*cp*gp*tp*cp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)-1H-benzimidazole-7-carboxamide2-(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)-1H-benzimidazole-7-carboxamide
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303