8FYY: Crystal structure of human PARP1 ART domain bound to inhibitor UKTT5 (compound 10)

PDB ID: 8FYYDownload
MMDB ID: 242247
PDB Deposition Date: 2023/1/27
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8FYY: monomeric; determined by author
Molecular Components in 8FYY
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 1, Processed C-terminus
(Gene symbol: PARP1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
beta-D-fructofuranosebeta-D-fructofuranose
3
1
2-(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)-1H-benzimidazole-7-carboxamide2-(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)-1H-benzimidazole-7-carboxamide
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303