8FYT: LSD-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex

PDB ID: 8FYTDownload
MMDB ID: 246885
PDB Deposition Date: 2023/1/26
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.64  Å
Source Organism:
Similar Structures:
Biological Unit for 8FYT: tetrameric; determined by author and by software
Molecular Components in 8FYT
Label Count Molecule
Proteins (4 molecules)
1
Soluble Cytochrome B562,5-hydroxytryptamine Receptor 1a,5-hydroxytryptamine Receptor 1A
(Gene symbol: HTR1A)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
(Gene symbol: GNAI1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide(8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide
2
1
[(2R)-1-[oxidanyl-[(2R,3R,5S,6R)-2,3,5,6-tetrakis(oxidanyl)-4-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-3-tetradecanoyloxy-propan-2-yl] (5E,8E)-hexadeca-5,8,11,14-tetraenoate[(2R)-1-[oxidanyl-[(2R,3R,5S,6R)-2,3,5,6-tetrakis(oxidanyl)-4-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-3-tetradecanoyloxy-propan-2-yl] (5E,8E)-hexadeca-5,8,11,14-tetraenoate
3
2
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303