National Center for
Biotechnology Information

8FX5: Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline

PDB ID:

MMDB ID:

235419

PDB Deposition Date:

2023/1/23

Updated in MMDB:

2023/09

Experimental Method:

electron microscopy

Resolution:

2.45 Å

Source Organism:

Mus musculus▼

Taxonomy	Molecule
Mus musculus	A
Homo sapiens	R, B, G, H

Similar Structures:

Biological Unit for 8FX5: pentameric; determined by author

Molecular Components in 8FX5
Label	Count	Molecule
Proteins (5 molecules)
R	1	Muscarinic Acetylcholine Receptor M4
B	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
G	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
H	1	Antibody Fragment Scfv16
A	1	Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Chemicals and Non-standard biopolymers (2 molecules)
1	2	xanomeline

* Click molecule labels to explore molecular sequence information.

Citing MMDB