8FX3: Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to Immucillin-GP, showing the structure of the complete active site in its open conformation

PDB ID: 8FX3Download
MMDB ID: 233066
PDB Deposition Date: 2023/1/23
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.31  Å
Source Organism:
Similar Structures:
Biological Unit for 8FX3: dimeric; determined by author and by software (PISA)
Molecular Components in 8FX3
Label Count Molecule
Proteins (2 molecules)
2
Hypoxanthine-guanine Phosphoribosyltransferase
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTERPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303