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8FX2:
Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to Immucillin-HP
PDB ID:
8FX2
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MMDB ID:
233065
PDB Deposition Date:
2023/1/23
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
1.54 Å
Source Organism:
Trypanosoma cruzi strain CL Brener
Similar Structures:
VAST+
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Biological Unit for 8FX2: dimeric; determined by author and by software (PISA)
Molecular Components in 8FX2
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Hypoxanthine-guanine Phosphoribosyltransferase
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303